Protein metabolism in marine animals: the underlying mechanism of growth

first_imgGrowth is a fundamental process within all marine organisms. In soft tissues, growth is primarily achieved by the synthesis and retention of proteins as protein growth. The protein pool (all the protein within the organism) is highly dynamic, with proteins constantly entering the pool via protein synthesis or being removed from the pool via protein degradation. Any net change in the size of the protein pool, positive or negative, is termed protein growth. The three inter-related processes of protein synthesis, degradation and growth are together termed protein metabolism. Measurement of protein metabolism is vital in helping us understand how biotic and abiotic factors affect growth and growth efficiency in marine animals. Recently, the developing fields of transcriptomics and proteomics have started to offer us a means of greatly increasing our knowledge of the underlying molecular control of protein metabolism. Transcriptomics may also allow us to detect subtle changes in gene expression associated with protein synthesis and degradation, which cannot be detected using classical methods. A large literature exists on protein metabolism in animals; however, this chapter concentrates on what we know of marine ectotherms; data from non-marine ectotherms and endotherms are only discussed when the data are of particular relevance. We first consider the techniques available to measure protein metabolism, their problems and what validation is required. Protein metabolism in marine organisms is highly sensitive to a wide variety of factors, including temperature, pollution, seasonality, nutrition, developmental stage, genetics, sexual maturation and moulting. We examine how these abiotic and biotic factors affect protein metabolism at the level of whole-animal (adult and larval), tissue and cellular protein metabolism. Available gene expression data, which help us understand the underlying control of protein metabolism, are also discussed. As protein metabolism appears to comprise a significant proportion of overall metabolic costs in marine organisms, accurate estimates of the energetic cost per unit of synthesised protein are important. Measured costs of protein metabolism are reviewed, and the very high variability in reported costs highlighted. Two major determinants of protein synthesis rates are the tissue concentration of RNA, often expressed as the RNA to protein ratio, and the RNA activity (kRNA). The effects of temperature, nutrition and developmental stage on RNA concentration and activity are considered. This chapter highlights our complete lack of knowledge of protein metabolism in many groups of marine organisms, and the fact we currently have only limited data for animals held under a narrow range of experimental conditions. The potential assistance that genomic methods may provide in increasing our understanding of protein metabolism is described.last_img read more

The Legendary Soul Singer, Charles Bradley, Dies At 68

first_imgToday, the world is mourning the loss of the legendary soul singer, Charles Bradley, who died today at the age of 68 years old. In October of last year, the iconic musician announced that he had been diagnosed with stomach cancer and had canceled his tour dates, later returning to the road this past summer with an extensive tour. Earlier in September, Bradley was forced to cancel his upcoming tour dates after the cancer had spread to his liver.The Brooklyn-raised Daptone Records singer has been a cornerstone of the funk/soul revival in recent years, and is nothing short of being a positive force and inspiration both on stage and in the studio. Bradley was scheduled to play all over the world from September through December, including a gig this weekend in Brooklyn at OctFest, dates in South America and Europe, Suwannee Hulaween, and a New Year’s Eve support gig for My Morning Jacket in Colorado.You can read the statement via Bradley’s official Facebook page below. Rest in peace, Mr. Bradley. You will be missed. It is with a heavy heart that we announce the passing of Charles Bradley.Mr. Bradley was truly grateful for all the love he’s received from his fans and we hope his message of love is remembered and carried on. Thank you for your thoughts and prayers during this difficult time.In lieu of flowers, donations may be made to the following organizations:– All-Stars Project:– Music Unites: http://www.musicunites.orglast_img read more

Daily Dirt: Contour Makes a Comeback, Astral’s New Sticky Rubber, Jackson Kayaks on NBC Sports, and More!

first_imgAll the outdoor industry dirt that’s fit to print, from the editors of Blue Ridge Outdoors magazine.Jackson Kayaks Premiers Season 3: Extreme Kayak Fishing ChallengeProducers of Seaguar’s Extreme Kayak Fishing Challenge with Jim Sammons launched their third season on NBC Sports Wednesday, April 9. The show follows Jim Sammons on journeys to exotic locations catching massive game fish from his kayak.The first episode follows Sammons and Luther Cifers of YakAttack to Rancho Leonero in the East Cape of Baja where they target the ultimate kayak fishing game fish – the marlin.Extreme Kayak Fishing Challege with Jim Sammons is presented by Seaguar and will air weekly for 13 weeks on NBC Sports, featuring top fishing destinations including North Carolina. Footage will also be used for Jackson Kayak’s Kayak Fishing Show – airing all year on The World Fishing Network.CONTOUR Returns to POV Camera MarketBased in the heart of Utah’s Wasatch Mountains, CONTOUR cameras are back on the market. These POV action cameras were known for sleek, low profile design, easy-to-operate controls, and a durable proprietary rail connection system for use in the water, snow, dirt or flying through the air. For more information on the latest products, team activities and dealer locations, visit“The aim is clear—we want to create a world class company to support this world class product,” said Danny Lysenko, CEO. “We’ll continue the tradition of being at the forefront of innovation and bringing to market beautifully simple, yet ultimately professional cameras.”CONTOUR plans to launch new cameras that feature a one-touch locking record switch.Those affected by warranty issues should contact [email protected]Screen shot 2014-04-03 at 1.16.05 PMAstral Introduces New Sticky RubberAstral, known for its rich history and key innovations in paddlesports equipment, is expanding its award-winning footwear collection with a new outsole that utilizes a propriety sticky G.14 rubber. The company says its new rubber will surpass the performance of any outsole previously available to paddlers.astral brewerAstral’s new soles — which will be on the Brewer and new women’s specific Brewess – feature increased surface contact and added siping to improve grip and shed mud more effectively. They are also lightweight with classic takeout-to-table good looks. They feature zero-drop midsoles with a wide toe box for balance and stability. The minimalist upper is constructed with Cordura nylon and airmesh for abrasion resistance, lightweight, and fast drying. (MSRP $99.95)Snow Sports Retail Sales Up in All Regions Through FebruarySnowSports Industries America (SIA), the snow sports industry’s member-owned trade association, and Leisure Trends, an NPD Group Company have released SIA RetailTRAK numbers for August through February 2014, based on data collected from the Point of Sale systems of more than 1,200 snow sports retailers.The snow sports retail market finished February up 5 percent in units sold and up 7 percent in dollars sold to $3.3B for all equipment, apparel and accessories. Snow sports retailers brought in $218M more dollars through February this season compared to August to February 2012/2013. Big sellers in the south included helmets, goggles, handwear and socks; while backcountry accessories led the growth in the West. Snowshoe sales are up 12 percent in units sold to 98K units and 14 percent in dollars to over $14 million sold through February.Nominate Someone for the 40Under405A4_SGB_40U40_2014_200hThe SportsOneSource Group has opened the nominating process for the 7th annual SGB 40 Under 40 Awards.  Nominations are open to anyone born after January 1, 1974 that is working in the sporting goods, action sports, outdoor, snow sports or bicycle industry.  Nominations close May 16, 2014.  Finalists will be honored in SGB magazine this summer. To nominate someone for this unique award, go to Slater Exits QuiksilverQuiksilver and world-champion surfer Kelly Slater ended their 23-year partnership effective April 1, and according to sources, he has partnered with the Kering Group — owner of Puma and Volcom — to launch his own brand.Slater said on Facebook: “As I contemplate the amazing opportunities I’ve had in life and the amount of good fortune I’ve encountered along the way, I’m excited to announce today that I’m embarking on a new journey. For years I’ve dreamt of developing a brand that combines my love of clean living, responsibility and style. The inspiration for this brand comes from the people and cultures I encounter in my constant global travels and this is my opportunity to build something the way I have always wanted to. So I am excited to tell you that I’ve chosen The Kering Group as a partner. They share my values and have the ability to support me in all of my endeavors. I look forward to exploring all of the new opportunities this partnership will provide, but this hasn’t happened by chance, nor has it happened without an incredible amount of work by a few key individuals. As I embark on this new journey, I am sticking to my gut instincts and the belief that your dreams can become reality with the right intentions. I look forward to sharing more about it soon.”Quiksilver said it had reached many milestones with Slater over the years, including 11 ASP World Titles, countless World Champion Tour victories and collaborations in developing his Quiksilver collection.Quiksilver first signed the 18 year-old Slater in 1990 and his legacy includes not only decades of competition but also a deep history of product collaborations that left its mark on the surf industry. His influence will be seen in Quiksilver’s upcoming partnership with REPREVE Fabrics and the brand’s commitment to working with recycled materials.last_img read more

Research Making the West of it

first_imgTo access this article REGISTER NOWWould you like print copies, app and digital replica access too? SUBSCRIBE for as little as £5 per week. Would you like to read more?Register for free to finish this article.Sign up now for the following benefits:Four FREE articles of your choice per monthBreaking news, comment and analysis from industry experts as it happensChoose from our portfolio of email newsletterslast_img

Crowdfunding for ‘made in Indonesia’ test kits reaches target

first_imgA crowdfunding effort for locally produced real-time polymerase chain reaction (RT-PCR) test kits, for more reliable COVID-19 detection, reached its donation target of Rp 10 billion (US$649,329) on Sunday.The fund, initiated by venture capital firm East Ventures in a collaborative movement called Indonesia Pasti Bisa, will be used to produce 100,000 RT-PCR test kits. More than 2,000 individuals and corporations such as unicorn companies Tokopedia and Traveloka, as well as venture capitalists AC Ventures, Triputra Group and Samora Group donated to the fund.“The huge participation is an example of solidarity to fight the COVID-19 pandemic. Thank you to all donors, volunteers and partners,” said East Ventures cofounder and managing partner Willson Cuaca in a written statement on Monday. One of the test manufacturers Bio Farma previously stated that it would produce 2,000 test kits to accommodate 50,000 tests in May. However, a surge in global demand caused some production materials to be delayed so the production had to wait until all the materials had arrived in Indonesia.“We are consistent with the objective of producing 100,000 test kits to detect COVID-19 and hopefully reduce our import dependency on test kits,” said Honesti Basyir, president director of Bio Farma.The government recently secured 50,000 PCR test kits and planned to conduct 1,000 PCR tests per day to expedite the detection of the virus in individuals. Doni Monardo, head of the national COVID-19 rapid response task force, conveyed the plan following President Joko “Jokowi” Widodo’s order.The donations for producing the test kits began on March 30, after homegrown genomics technology company Nusantics was appointed by the Agency for the Assessment and Application of Technology (BPPT) to make the test kit prototypes based on samples from Indonesian nationals.Nusantics, which was established in 2019, had received an undisclosed seed funding from East Ventures prior to the appointment in March. (eyc)Topics :last_img read more

Mohave Valley Raceway celebrates 25th, Baca celebrates IMCA Modified feature win

first_imgChaz Baca was the $1,500 IMCA Modified winner at Mohave Valley Raceway’s 25th anniversary event Saturday night. (Photo by Rona Philpott)MOHAVE VALLEY, Ariz. (April 14) – Consistency has Chaz Baca on top of IMCA Speedway Motors Weekly Racing National and Larry Shaw Race Cars Western Region point standings.Speed put him in victory lane Saturday at Mohave Valley Raceway’s 25th anniversary special … twice.Baca led the last 10 laps in winning the IMCA Modified feature, and $1,500. He also scored the $1,000 checkers in a borrowed dwarf car.“This race has been on our schedule for about a month,” he said following the four-hour tow home to Mesa. “It’s the first time I’ve won two big money races on the same night. It feels pretty good. We were super excited.”Baca ran second in his heat, started the main event from eighth and was up to second just after midway in the 25-lapper.He was reeling in pole starter Bill McIntosh before a caution, then took the lead after the ensuing restart.Mike Kirby ended in second with Leland Hibdon, Clint Reichenbach and McIntosh completing the top five.Already on the Fast Shafts All-Star Invitational ballot, Baca won for the second time this season. He’s finished in the top five in nearly half of his 28 starts thus far in 2018.“We’re trying to be consistent and be in the top three, top five every race. It felt really good this weekend, especially the money,” said Baca, looking to put part of that payday toward a 2018 Shaw.Feature results – 1. Chaz Baca; 2. Mike Kirby; 3. Leland Hibdon; 4. Clint Reichenbach; 5. Bill McIntosh; 6. Ryan Roath; 7. Ronnie Meyer Jr.; 8. Brenda Kirby; 9. Bryan Wulfenstein; 10. Billy Wormsbecker; 11. Steve Simpson, Jr.; 12. Adam Marx; 13. Randy Ahrns; 14. John Clemens; 15. Bud Sturgis; 16. Paul Hurns; 17. Cameron Williams; 18. Kelsie Foley; 19. Bobby Ziello; 20. Patrick McIntosh.last_img read more


first_img– START TODAY AT VRYMAN’S ERVIN COURT, NEW AMSTERDAMTHE first of seven basketball clinics to be staged across the country by the Brusches Basketball foundation begins today  with the first such clinic for 50 primary school children in Berbice at the Vryman’s Erving basketball court in New Amsterdam, Berbice.The clinic, which will be conducted by United States-based former national captain, James Brusche and his brother Mike, who is a former national captain and coach, will be staged from 13.00hrs. They are here for the staging of their biennial tournament which, this year, has targeted Under-18 players from clubs across the country.Former national player Shauna Chester will be assisting the foundation in the clinics across Guyana as others are set for the East Coast Demerara, Georgetown, Linden and Kwakwani.From 13.00hrs, the clinic bounces off at the Vryman’ Erving basketball court in New Amsterdam, and tomorrow, the first of two clinics for 50 primary school children on the East Coast will be held at the Plaisance Guardians basketball court from 11.00hrs.After that, the second clinic will be at the Burnham Court in Georgetown for another 50 primary school children in that catchment area, starting at 13.00hrs.On Thursday, the clinic is set for the Mackenzie Sports Club hard court from 13.00hrs and the last clinic will be staged next Monday at the Kwakwani basketball court for players in that area.The Ministry of Education in the respective areas was contacted to ensure the primary school children in their communities receive the coaching from the former national players who see this as a means of giving back to the development of the sport at the basic levels.last_img read more

David Whitley, Wellington: Dec. 11, 1947 – Jan. 15, 2013

first_imgDavid WhitleyDavid Whitley, of Wellington, died Tuesday, January 15, 2013 at Via Christi-St. Francis in Wichita at the age of 65.David was born the son of Derrel and Goldie (Wright) Whitley on Thursday, December 11, 1947 in Wellington.On December 10, 1995, David and Kenta Guisinger were united in marriage in Ark City. Together they celebrated 17 years of marriage.David served in the United States Navy during Vietnam and later worked as a machinist and CNC operator.Survivors include his wife, Kenta Whitley of Wellington, son, Kenneth Young of Ark City, daughter, Kathy Cooper of Wellington, son, Jeremy Young of Caldwell, half brother, Richard Whitley of Wellington, and aunts, Pat Thomas and Wanda Spainhour both of Wellington.He was preceded in death by his parents and brother, Jerry Whitley.Memorial services for David will be at 10:30 a.m., Tuesday, January 22, 2013 in the First Free Will Baptist Church, 1219 North Plum, Wellington, Kans.Interment will follow at the Prairie Lawn Cemetery in Wellington.Memorials have been established in his loving memory with the Avenue of Flags, P.O. Box 339, Wellington, Kans. 67152 or Heartland Lions Eye Bank, 9415 East Harry Street, Wichita,  67207. Contributions can be mailed or left with the funeral home.To share a memory or leave condolences, please visit are by Day Funeral Home & Crematory, Wellington.last_img read more